Thanks Breck, that's what I thought...
Well looks like the only way to get the desired affect (though not directly from within Sybase) may be one of the following:
1.) Override the Sybase DB-login process to perform a secondary-authentication/check (via use of the Sybase DB's "post_login_procedure" and/or "login_procedure" options) and tie it in with something 3rd-party or custom extended stored procedure that could then require BioID, CAC, or Token input.
2.) Use Integrated Login and make the O.S. Login process use some form of Multi-factor authentication - thus Sybase still doesn't do anything special and instead puts the onus on the O.S. login process to provide/enforce multi-factor authentication.